Unlock Protein Regulation with MtoZ Biolabs Quantitative Ubiquitinomics Service
Quantitative ubiquitinomics service provides a specialized solution for the precise identification, quantification, and characterization of ubiquitinated proteins within complex biological samples. MtoZ Biolabs integrates mass spectrometry-based ubiquitinomics solutions with advanced technologies, utilizing Orbitrap Fusion Lumos, Q Exactive HF, and Orbitrap Exploris systems. These state-of-the-art platforms, combined with Nano-LC systems and optimized fragmentation techniques (HCD, ETD), enable high-resolution detection of ubiquitin-modified peptides, even at low abundances.
Ubiquitination, characterized by the attachment of ubiquitin to lysine residues on target proteins, is marked by a characteristic K-ε-GG motif and a mass shift of approximately 114.1 Da. This unique modification is de...